THURSDAY OCTOBER 18th
8h45-9h00: WELCOME ADDRESS – Maxime Bouchard
SESSION 1: NORMAL ADULT AND CANCER STEM CELLS – Chair : Véronique Maguer-Satta
9h00-9h30 : Guy Sauvageau, Université de Montréal, IRIC, Canada. “New Strategies for Targeting Leukemia Stem Cells.”
9h30-10h00 : Michel Aurrand-Lions, Marseille, France. “Adhesive Cues Involved in Normal or Pathological Stem and Progenitor Cell Maintenance”
10h00-10h15 : Short talk: Boris Guyot, Centre de Recherche en Cancérologie de Lyon, Lyon, France. “A CD10-Score Reflects Tumor Content in Stem-like Cells and Predicts Patient Outcome in Solid Cancer”
10h15-10h30 : Short talk: Heather Duncan, The Research Institute of the McGill University Health Centre, Montréal, Canada. “G protein-Coupled Receptor 56 (GPR56/ADGRG1) as a Potential Functional Regulator of Normal and Leukemic Human Stem Cells”
10h30-11h00 : Coffee Break
11h-11h30 : Connie Eaves, Terry Fox Laboratory, Vancouver, Canada. “Human Breast Cancer – Starting from the Beginning”
11h30-12h00 : Julie Gavard, CNRS, Nantes, France. “Paracrine Interactions between Cancer Stem-like Cells and Endothelial Cells in Brain Tumors”
12h00-14h00 Lunch Break
SESSION 2: ADULT STEM CELLS IN HEALTH AND DISEASE – Chair : Bénédicte Chazaud
14h00-14h30: Peter Dirks, Sickkids, Toronto, Canada. “Manipulating the Brain Tumour Hierarchy“
14h30-15h00: Christian Dani, Institut Valrose, Nice, France. “Human Adipose Stem Cells Derived from Adipose Tissues and iPSC: Characterization and Therapeutic Potential”.
15h00-15h15 : Short talk: Mathieu Tremblay, Goodman Cancer Research Centre and Department of Biochemistry, McGill University, Montréal, Canada. “Normal and Cancerous Stemness is Regulated by a Gata3/Bmp Axis in the Prostate”.
15h15-15h30 : Short talk: Ryo Fujita, Lady Davis Institute for Medical Research and Department of Human Genetics, McGill University, Montréal, Canada. “The Orphan Adhesion G-protein Coupled Receptor GPR116 Regulates Muscle Stem Cell Quiescence and Self-Renewal”.
15h30-16h00 : Michael Rudnicki, Ottawa Hospital Research Institute, Ottawa, Canada. “Molecular Regulation of Muscle Stem Cell Function”
16h00-16h30 : Coffee Break
16h30-17h00 Freda Miller, Sickkids, Toronto, Canada. “Cellular Mechanisms Underlying Adult Mammalian Digit Tip Regeneration”
17h00-17h30 Alex Gregorieff, Research Institute of the McGill University Health Centre (RI-MUHC), McGill, Montréal, Canada. “Role of Yap in Damage-Induced Intestinal Stem Cell Plasticity.”
17h30-19h30 : Poster Session/ « Apéritif »
FRIDAY OCTOBER 19th
SESSION 3: DEVELOPMENTAL PROGENITOR AND PLURIPOTENT STEM CELLS – Chair: Maxime Bouchard
9h00-9h30 : Andras Nagy, The Lunenfeld-Tanenbaum Research Institute, Toronto, Canada. “Engineering a Safe and Allo-tolerated Pluripotent Stem Cell Line; a Global Source for Off-the-Shelf Therapeutic Cell Products”
9h30-10h00 : Majlinda Lako, Institute of Genetic Medicine, Newcastle University, UK. “Making Retinal Organoids in the Lab: a Voyage of Discovery”
10h00-10h15 : Short talk: Awais Javed, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Canada. “Pou2f1/2 Regulates the Timing of Cone Photoreceptor Production by Negatively Repressing the Rod-promoting Factor Nrl”.
10h15-10h30 : Short talk: Seerat Elahi, Department of Pathology and Anatomical Sciences, State University of New York at Buffalo, USA. “Differential Expression of Ars2 Guides Germ Layer Fate Decisions”.
10h30-11h00 : coffee break
11h00-11h30 : Michael Shen, Department of Genetics & Development, Columbia University, New York, U.S.A. “Progenitor Cells and the Origin of Prostate Cancer”
11h30-12h00 : Claire Chazaud, GReD – Genetics, Reproduction & Development, Clermont Ferrand, France. “Cell Lineage Differentiation in the Blastocyst: the Emergence of the Plutipotent Epiblast”
12h00-14h00 Lunch break & Poster session
14h00-15h00: Keynote lecture – Shahragim Tajbakhsh, Institut Pasteur, Paris, France. “Developmental and Postnatal Roles of Stem Cells and Their Niche”
SESSION 4: EMERGING CONCEPTS AND INNOVATIVE TECHNOLOGIES – Chair: Colin Crist
15h-15h30 : Antonio del Sol Mesa, University of Luxembourg, Luxembourg. “Single-cell Systems Biology Approaches to Stem Cell Research and Regenerative Medicine”
15h30-15h45 : Short talk: Carla Frau, Centre de Recherche en Cancérologie de Lyon, Lyon, France. “Unveiling the Mechanism of the RNA-binding Protein Musashi1 in Stemness and Drug Resistance of Intestinal Stem Cells”.
15h45-16h00 : Short talk: Marco Zanini, Institut Curie, CNRS UMR 3347, Orsay, France. “Atoh1 Requires Primary Cilia for the Expansion of Granule Neuron Progenitors by Modulating Centriolar Satellites”.
16h00-16h30 : coffee break
16h30-17h00 : Carl Ernst, The Douglas Hospital Research Centre, McGill University, Montreal, Canada. “Major Boost in Dopamine and Tyrosine Hydroxylase in Ventral Midbrain Dopaminergic Cells Derived from Human Skin by L-type Calcium Stimulation”
17h00-17h30 : Mohan Malleshaiah, Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Canada. “Unraveling the Stem Cell State Specific Regulatory Networks”
17h30-17h45 : Poster awards and closing remarks – Guy Mouchiroud