Program

THURSDAY OCTOBER 18th

8h45-9h00: WELCOME ADDRESS – Maxime Bouchard

SESSION 1: NORMAL ADULT AND CANCER STEM CELLS – Chair : Véronique Maguer-Satta

9h00-9h30 : Guy Sauvageau, Université de Montréal, IRIC, Canada.  “New Strategies for Targeting Leukemia Stem Cells.”

9h30-10h00 : Michel Aurrand-Lions, Marseille, France. “Adhesive Cues Involved in Normal or Pathological Stem and Progenitor Cell Maintenance”

10h00-10h15 : Short talk:  Boris Guyot, Centre de Recherche en Cancérologie de Lyon, Lyon, France. “A CD10-Score Reflects Tumor Content in Stem-like Cells and Predicts Patient Outcome in Solid Cancer”

10h15-10h30 : Short talk:  Heather Duncan, The Research Institute of the McGill University Health Centre, Montréal, Canada. “G protein-Coupled Receptor 56 (GPR56/ADGRG1) as a Potential Functional Regulator of Normal and Leukemic Human Stem Cells”


10h30-11h00 : Coffee Break


11h-11h30 : Connie Eaves, Terry Fox Laboratory, Vancouver, Canada. “Human Breast Cancer – Starting from the Beginning”

11h30-12h00 : Julie Gavard, CNRS, Nantes, France. “Paracrine Interactions between Cancer Stem-like Cells and Endothelial Cells in Brain Tumors”


12h00-14h00 Lunch Break


SESSION 2: ADULT STEM CELLS IN HEALTH AND DISEASE – Chair : Bénédicte Chazaud

14h00-14h30: Peter Dirks, Sickkids, Toronto, Canada.  “Manipulating the Brain Tumour Hierarchy

14h30-15h00: Christian Dani, Institut Valrose, Nice, France. “Human Adipose Stem Cells Derived from Adipose Tissues and iPSC: Characterization and Therapeutic Potential”.

15h00-15h15 : Short talk:  Mathieu Tremblay, Goodman Cancer Research Centre and Department of Biochemistry, McGill University, Montréal, Canada.  “Normal and Cancerous Stemness is Regulated by a Gata3/Bmp Axis in the Prostate”.

15h15-15h30 : Short talk:  Ryo Fujita, Lady Davis Institute for Medical Research and Department of Human Genetics, McGill University, Montréal, Canada.  “The Orphan Adhesion G-protein Coupled Receptor GPR116 Regulates Muscle Stem Cell Quiescence and Self-Renewal”.

15h30-16h00 : Michael Rudnicki, Ottawa Hospital Research Institute, Ottawa, Canada. “Molecular Regulation of Muscle Stem Cell Function”


16h00-16h30 : Coffee Break


16h30-17h00 Freda Miller, Sickkids, Toronto, Canada. “Cellular Mechanisms Underlying Adult Mammalian Digit Tip Regeneration”

17h00-17h30 Alex Gregorieff, Research Institute of the McGill University Health Centre (RI-MUHC), McGill, Montréal, Canada.  “Role of Yap in Damage-Induced Intestinal Stem Cell Plasticity.”


17h30-19h30 : Poster Session/ « Apéritif »


FRIDAY OCTOBER 19th

SESSION 3: DEVELOPMENTAL PROGENITOR AND PLURIPOTENT STEM CELLS – Chair: Maxime Bouchard

9h00-9h30 : Andras Nagy, The Lunenfeld-Tanenbaum Research Institute, Toronto, Canada.  “Engineering a Safe and Allo-tolerated Pluripotent Stem Cell Line; a Global Source for Off-the-Shelf Therapeutic Cell Products”

9h30-10h00 :  Majlinda Lako, Institute of Genetic Medicine, Newcastle University, UK. “Making Retinal Organoids in the Lab: a Voyage of Discovery”

10h00-10h15 : Short talk:  Awais Javed, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Canada. “Pou2f1/2 Regulates the Timing of Cone Photoreceptor Production by Negatively Repressing the Rod-promoting Factor Nrl”.

10h15-10h30 : Short talk:  Seerat Elahi, Department of Pathology and Anatomical Sciences, State University of New York at Buffalo, USA.  “Differential Expression of Ars2 Guides Germ Layer Fate Decisions”.


10h30-11h00 : coffee break


11h00-11h30 : Michael Shen, Department of Genetics & Development, Columbia University, New York, U.S.A.  “Progenitor Cells and the Origin of Prostate Cancer”

11h30-12h00 : Claire Chazaud, GReD – Genetics, Reproduction & Development, Clermont Ferrand, France. “Cell Lineage Differentiation in the Blastocyst: the Emergence of the Plutipotent Epiblast”


12h00-14h00 Lunch break & Poster session


14h00-15h00: Keynote lecture – Shahragim Tajbakhsh, Institut Pasteur, Paris, France. “Developmental and Postnatal Roles of Stem Cells and Their Niche”

SESSION 4: EMERGING CONCEPTS AND INNOVATIVE TECHNOLOGIES – Chair: Colin Crist

15h-15h30 : Antonio del Sol Mesa, University of Luxembourg, Luxembourg. “Single-cell Systems Biology Approaches to Stem Cell Research and Regenerative Medicine”

15h30-15h45 : Short talk:  Carla Frau, Centre de Recherche en Cancérologie de Lyon, Lyon, France. “Unveiling the Mechanism of the RNA-binding Protein Musashi1 in Stemness and Drug Resistance of Intestinal Stem Cells”.

15h45-16h00 : Short talk:  Marco Zanini, Institut Curie, CNRS UMR 3347, Orsay, France. “Atoh1 Requires Primary Cilia for the Expansion of Granule Neuron Progenitors by Modulating Centriolar Satellites”.


16h00-16h30 : coffee break


16h30-17h00 : Carl Ernst, The Douglas Hospital Research Centre, McGill University, Montreal, Canada. “Major Boost in Dopamine and Tyrosine Hydroxylase in Ventral Midbrain Dopaminergic Cells Derived from Human Skin by L-type Calcium Stimulation”

17h00-17h30 : Mohan Malleshaiah, Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Canada. “Unraveling the Stem Cell State Specific Regulatory Networks”


17h30-17h45 :  Poster awards and closing remarks – Guy Mouchiroud


A PDF version of the scientific program and abstract booklet is here: SCDC2018-Program_Abstract Booklet

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